Windows XP up to Windows 10 Fall Creator update 1709 (16299.xx) (anything higher is at your own risk)
NVIDIA, AMD, Intel GPUs
Microsoft .NET Framework 3.0 or higher
You should disconnect your internet or block Windows Updates.
DDU should be used when having a problem uninstalling/installing a driver or when switching GPU brand.
DDU should not be used every time you install a new driver unless you know what you are doing.
The tool can be used in Normal mode but for absolute stability when using DDU, Safemode is always the best.
If you are using DDU in normal mode, Clean, reboot, clean again, reboot.
Make a backup or a system restore (but it should normally be pretty safe).
It is best to exclude the DDU folder completely from any security software to avoid issues.
Official Page: https://www.wagnardsoft.com/forums/viewtopic.php?f=5&t=976